Lupus vulgaris of centrofacial area - a peculiar presentation

Lupus vulgaris is a cutaneous manifestation of Mycobacterium tuberculosis infection. It assumes various clinical forms including plaque, ulcerative, hypertrophic, vegetative, papular and nodular type. We here present an unusual case of a ten-year-old girl diagnosed as hypertrophic lupus vulgaris of centrofacial area including nose. Histopathological examination and bacteriological studies were carried out to establish the diagnosis. Unlike plaque type, hypertrophic variety is quite uncommon and only few cases have been reported. Its peculiar appearance on the face which is hardly described in previous literatures and well response to antitubercular therapy prompted us to report it

Anticuerpos contra el virus de la inmunodeficiencia humana en lupus erimatoso generalizado / Antibodies aginst human inmunodeficiencuy virus in generalized lupus erythematous

Posterior al estudio de un paciente masculino bisexual con cuadro clínico sugestivo de síndrome de Inmunodeficiencia Adquirida, con anticuerpos contra Virus de la Inmunodeficiencia Humana (VIH) por métodos inmunoenzimático (ELISA) pero resultados negativos en las pruebas de anti-Env/Ccore e inmunofluorescencia indirecta y diagnóstico final de Lupus Eritematoso Generalizado (LEG), se estudiaron setenta pacientes con LEG, para determinar en ellos la frecuencia de resultados positivos en la detección de anticuerpos séricos contra VIH por ELISA. Encontrándose positivos el 5.7 por ciento, lo cual se redujo a 2.8 por ciento al repetir la prueva en una segunda muestra de los previamente positivos y estos fueron negativos a anti-Env/Core e inmunofluorescencia indirecta contra VIH. Presentamos resumen clínico del caso que motivó la realización del presente trabajo

After studying a bisexual male with a clinical picture suggestive of AIDS a positive ELISA test for antibodies against the Human Immunodeficiency Virus (HIV), but negative results on indirect immunofluorescence testing, as well, as absence of core and envelope tnvantibodies by ELISA, and who later turned out to have Systemic Lupus Erythematosus (SLE) which become asymptomatic on corticosteroid therapy, we decided to test 70 patients with SLE for HIV antibodies. Four of them (5.6%) were positive by ELISA, but on a repeated test only 2 (2.8%) remanined positive, and their serawas tested by indirect immunofluorescence. They were negative, as was the ELISA test for core and envelope HIV antibodies. We conclude that the possibility of more such cases, of SLE mimicking AIDS, should be kept in mind, including the occurrence of false positive ELISA tests in such patients.